PREdS Study

Data collection for the PREdS Study has now finished, keep an eye out for results and any follow-ups!

The Perioperative Replacement of Exogenous Steroids (PREdS Study)

PREds is a trial designed by a team from the Severn Trainee Anaesthetic Research Network (STAR) to assess management of perioperative steroids.

Key Dates: The study window will run from 26/09/20022 to 04/12/2022

A prospective, multicentre study to assess the number of patients presenting for elective, urgent or emergency procedures who are taking long-term oral steroids and determine how perioperative steroid replacement is currently being managed.

How to get involved: Head here for more info

Downloads:

Follow the link above for more documentation and downloads

Perioperative Paracetamol Waste Audit

Perioperative Paracetamol Waste Audit

Update

A collaboration with WEAN (Welsh Anaesthetic Environmental Network) and
TRA2SH (Trainee-Led Research and Audit in Anaesthesia for Sustainability in
Healthcare)

Get involved with our latest audit project looking at waste that could be avoided by
administering pre-operative oral Paracetamol instead of intraoperative IV
paracetamol, including packaging waste, giving set and extra cost.


We are hoping to collaborate to collect more data and make a case that small
change can potentially prevent a significant amount of waste and save money.

Key Dates: Recruitment finished

How to get involved: Website

Downloads:

RAFT3: DALES

The 3rd RAFT national collaborative project involving all networks was DALES, Drug Allergy Labels in the Elective Surgical population.

It was a three-day study commencing mid-2018 comprising Patient Questionnaire, Anaesthetist Survey and Patient Follow-Up on the day.

Link

The Study

DALES was designed to evaluate the prevalence of patient-reported and documented allergy to drugs relevant to anaesthesia and to learn more about anaesthetists’ knowledge and attitudes to allergy.

The study took the form of questionnaires / interviews for quantitative analysis. This was a cross sectional, observational and descriptive study design:

Patient Questionnaire

This occurred across the country in multiple sites over 3 days within a 6-week study window. When patients attended hospital for planned surgery they were consented for a questionnaire about their allergies. Baseline data was collected from all patients attending for elective surgery, regardless of allergy status. Data was collected electronically at the bedside using the REDCap system and securely stored

Targeted Patient Follow-Up

Patients who reported allergy to B-lactams or opioids were followed up post-op if they were due to receive these drugs. An investigator reviewed the anaesthetic and drug charts and note how the drug allergy was documented and what was given. Any changes to the documentation of allergy were recordedAny episode of unexpected patient instability that took place in the peri-operative period was recorded

Anaesthetist Survey

All anaesthetists and prescribing anaesthetic practitioners working during the study period were invited to take part in a survey about attitudes to drug allergy labels in the elective perioperative setting

Which hospitals in Wales took part?

Cardiff and Vale UHB:  University Hospital of Wales

Collaborators:  Anna Williams, Jessica Phillips, Emily Murphy, Matthew Soanes, Laura Allen

PI:  Danielle Huckle

Abertawe Bro Morgannwg UHB:

Morriston, Singleton

Collaborators:  Nadine Jones, Benjamin O’Donovan, Harriet Pudge, Alexandra Cormack, Catherine Chapman, Sean O’Beirn

PI:  Nathan Tweed

Princess of Wales

Collaborators:  Tanya Smith, Mike Cooper

PI:  Rhidian Jones

Betsi Cadwaldr UHB: Wrexham Maelor

Collaborators:  Amanda Skingle, Jana Anandarajah, Nowfal Rahman

PI:  Andy Campbell

Hywel Dda UHB: Prince Philip, West Wales General

Collaborators:  Brigitte Baxter, Gareth James

PI:  Alun Thomas

Cwm Taf UHB: Royal Glamorgan, Prince Charles

Collaborators:

PI: Aneurin Bevan UHB:

Royal Gwent

Collaborators:  Alexander Photiou, Anthony Rimmer, Nicholas Gibson, Roisin Flanaghan, Nitin Bhalla

PI:  Tamas Szakamy

Neville Hall

Collaborators:  Pete Collett, Jake Moss, Helen Ross

PI:  Vincent Hamlyn

Publications

Published in December 2020:

https://www.sciencedirect.com/science/article/abs/pii/S0007091220306413

Published in July 2021:

https://bjanaesthesia.org/article/S0007-0912(21)00345-7/fulltext